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An 850 bp fragment surrounding exon 1 was replaced with a lacZ gene and neomycin selection cassette. Beta-galactosidase is expressed from this allele under the control of the endogenous promoter. FACS analysis on peritoneal macrophages derived from homozygous mice confirmed that no functional encoded protein was present on the cell surface. (J:76451)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
