Ccna1^tm1Djw

A 1.4 kb fragment including exon 1 and a portion of exon 2 was replaced by a PGK-hprt cassette. Northern blot analyses using probes for the 5' and 3' termini showed an absence of transcript in the testis of homozygous mutant mice.Normal protein was undetected by immunohistochemical staining. (J:51290)