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中文
在胚胎干细胞中表达的Cre重组酶，导致了包含新霉素基因的含681-837核苷酸的翼内肌显性区的剔除，这个区域来源于GenBank中作为X57111发布的鼠标cDNA序列。引入的缺失导致了框架突变。对纯合突变小鼠的总RNA提取物进行RT-PCR分析，未检测到正常转录本。用针对C端的抗体进行的 Western 分析在纯合突变小鼠中也未能检测到蛋白质。(来源：J:51666)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
