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中文
通过同源重组，将新霉素抗性基因 cassette 插入到 intron 1，并在 exon 1 的第 236 位引入了赖氨酸到谷氨酸的点突变 (K236Q)。对纯合突变动物脑组织的 Western blot 检测确认了蛋白质表达，酶学分析显示其对磷脂和 syntaxin 的结合能力和钙亲和性与野生型相似。(来源：J:76452)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
