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中文
ES细胞通过将一个LoxP位点插入经11号外显子上游，以及一个含诺卡因-胸腺嘧啶-激酶区的floxed序列插入下游，实现了构建。短暂在ES细胞中表达Cre重组酶，导致选择基因和11号外显子被剔除。11号外显子编码膜IV部分，存在于所有已知的剪接变体中。（来源：J:76715）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
