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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Nefl
tm1Jpj
Alias:
NF-L-
L-
NFL-
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基础信息
表型特征
文献报道
0.7千碱基的基因,包括exon 1,通过同源重组被替换了neo抗药性基因座。对纯合突变动物大脑和神经组织的Northern和Western印迹实验没有检测到基因表达,也没有检测到任何剪接异常的mRNA片段或蛋白片段。(来源:J:44421)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2180095
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入,基因内删除
--
1
5
35
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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