将一个无启动子的hygromycin-lacZ融合基因,带有转录终止子,插入βactin基因座的起始内含子中。在纯合突变体中检测到正常转录,表明融合基因在转录时偶尔被剪切,产生了一个功能减弱的等位基因。表达分析显示,整合事件并未导致β半乳糖苷酶的泛表达。(来源:J:46634)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1+
Targeted
插入
--
1
6
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部