在最后一个编码外显子的5'端插入了一个loxP位点,然后在该外显子的3'端紧接着插入了loxP位点加上抗氨苄青霉素的抗性基因座。这种突变位于编码转录活性必需motifs以及转录终止和poly(A)加尾序列的序列周围。(来源:J:66593)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
12
25

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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