这个转基因通过鼠垂体α亚基(Cga)基因的调控,表达Cre重组酶。该启动子在胚胎期9.5日的垂体原基中就开始活跃。Cre重组酶在垂体前叶和中间叶、心脏以及骨骼肌中检测到表达。在后叶、肺、肾、脑、肾上腺和性腺中,表达量较低或无。信息来源:(J:66897)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x SJL)F2
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17

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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