Log In|Sign Up
中文
这段基因的450bp，包括第4外显子和部分第5外显子，通过同源重组被一个新 cassette 替换，导致阅读框的移位和预测出首个64个氨基酸后蛋白质的截断。通过Southern blot和Western blot的分析，鉴定出了纯合突变的ES细胞，并且 Western blot确认了没有蛋白质产物产生。(来源：J:41941, J:44361)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
