在人类基因的arg566位置插入了一个由loxP位点引导的诺卡因抗性基因座,随后跟着一个终止密码子。对结肠、肾和肺的RNA进行Northern blot分析显示,这个等位基因产生了大约1%-4%的剪切片段转录本。(来源:J:53057)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd-Hprt1b-m3
Targeted
插入
--
1
6
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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