一种新霉素抗性基因座替换了exon 3以及其周边序列。对纯合小鼠脑组织的 Western blot 检测结果显示,编码蛋白无法检测到。(来源:J:33035)
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A neomycin resistance cassette replaced exon 3 and flanking sequences. Western blot analysis on brain lysates from homozygous mice confirmed that no detectable encoded protein was present. (J:33035)