一种新霉素抗性基因座替换了包含2-9号外显子的基因组片段。对纯合小鼠脑组织的 Western blot 检测显示,这个等位基因不表达可检测到的蛋白质。(来源:J:59180)
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A neomycin resistance cassette replaced a genomic fragment containing exons 2-9. Western blot analysis on brain lysates derived from homozygous mice demonstrated that no detectable protein was expressed from this allele. (J:59180)