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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Adra2a
tm1Bkk
Alias:
alpha2A-
alpha2A-ARKO
alpha2A-KO
alpha2A-AR
-
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基础信息
表型特征
文献报道
通过同源重组将新霉素 cassette 插入基因中,导致第三个跨膜域内出现了一个早终止密码子。靶向事件的确认通过Southern分析得到了验证。(来源:J:76317)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2179108
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
--
57
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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