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中文
这个转基因通过人类胶质纤维酸性蛋白(GFAP)启动子驱动Cre重组酶的表达。Cre介导的重组主要发生在中枢神经系统，影响星形胶质细胞、少突胶质细胞、室管膜和一些神经元。在肝脏的周边细胞中也有表达。转基因表达的发育始于胚胎期13.5日的前脑背侧和内侧区域。在成年小脑中，只有星形胶质细胞对GFAP或Cre重组酶有免疫反应。(来源：J:72509)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
