这个基因的Exon 2通过同源重组被替换了 neo 选择子。对突变动物的Northern blot分析显示,由于neo cassette的插入,检测到了更大量的RNA分子。 Western blot和免疫组化在雄性生殖腺(testis)的核提取物中未检测到蛋白质。(来源:J:47307)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入,基因内删除
--
1
1
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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