这个基因的Exon 2通过同源重组被替换了 neoemarkin表达载体。 Western blot结果显示,来自纯合突变动物的组织中没有表达。(来源:J:73798)
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Exon 2 of this gene was replaced with a neomycin expression cassette via homologous recombination. Western blot confirmed that expression was absent in tissue from homozygous mutant animals. (J:73798)