一种新霉素选择 cassette 替换了包含 exons 2 的 DNA 片段。对成年纯合小鼠大脑组织的结合分析证实,这个等位基因不产生功能蛋白。(来源:J:76020)
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A neomycin selection cassette replaced a DNA segment containing exon 2. Binding assays on brain sections of adult homozygous mice confirmed that no functional protein was expressed from this allele. (J:76020)