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中文
插入一个包含Bmi1基因，连接Pim1启动子、免疫球蛋白增强子以及小鼠源Moloney白血病病毒LTR的转录基因，会导致胸腺、骨髓和脾脏中BMI1的过量表达。启动子和增强子模块在淋巴细胞中能产生高水平的转录，且在早期发育阶段就活跃。 Northern blot分析在11.5日胚胎中检测到了3kb的丰度极高的转基因转录本。而分子杂交实验在12.5日的转基因胚胎中显示BMI1在全身范围内普遍存在并过量表达。(来源：J:24505)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
