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中文
在内皮10号 intron位置插入了一个loxP位点，然后在exon11处插入了loxP引导的诺姆西林筛选元件。通过暂时的Cre表达，ES细胞中去除了loxP引导的序列，随后产生了嵌合小鼠。最终的可遗传等位基因包含一个替换exon11并伴随内含子序列的loxP位点。免疫组化实验确认了这个等位基因未表达出可检测到的蛋白质。(来源：J:55695)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
