一种新霉素筛选 cassette 替换了编码 DNA 结合域的 DNA 片段。对双靶向 ES 细胞衍生的 RNA 进行 Northern blot 和 RT-PCR 分析后,结果显示这个等位基因没有产生可检测到的转录本。(来源:J:42409)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
插入,基因内删除
--
1
12
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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