在exon 3中插入了一种新霉素抗性基因。对来自纯合胚胎的胚胎纤维细胞进行的Northern blot分析显示,这个等位基因没有产生可检测到的转录物,细胞生长实验也证实了这个等位基因没有表达出功能蛋白。(来源:J:35071)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
插入
--
1
--
30

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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