在exon 3的上游插入了floxedneo抗药性 cassette,然后在exon后面插入了一个loxP位点。在产生嵌合小鼠之前,ES细胞中短暂表达Cre重组酶,剪除了neo cassette,使得exon 3被loxP位点包裹。(来源:J:73374)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
--
20

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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