一种新霉素抗性基因 cassette 替换了包含 exon 2 和周围序列的基因组片段。对杂合小鼠不同组织制备的离心液进行 Western blot 分析显示,所有检测的组织中,蛋白质水平均降低了 40-50% (来源:J:35137)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
插入,基因内删除
--
1
23
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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