该策略涉及去除信号序列,并将tau-lacZ PGK-neomycin cassette与起始密码子对齐融合。在纯合突变动物中,体内分子杂交未检测到内源性mRNA的表达。杂合胚胎通过与内源性表达模式相似的方式表达β-半乳糖苷酶。(来源:J:75288)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count