在基因的第3外显子插入了一个loxP引导的诺姆西林选择座。来自纯合小鼠肾和脑的RNA进行Northern blot分析显示,这个等位基因没有产生可检测到的转录本。对纯合小鼠肾提取物进行的Western blot分析证实,这个等位基因没有表达出蛋白质。(来源:J:72931)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
插入
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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