一种新霉素抗性基因座替换了编码细胞质酪氨酸磷酸酶区段的外显子。Northern印迹分析在3个月大同源突变雄性小鼠的多种组织中检测到了部分但非完整转录本,这些转录本的长度缩短了。同源突变小鼠胸腺细胞表面也检测到了部分蛋白质,其表达量相较于内源性蛋白有所降低。(引用文献:J:42273, J:119456)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入,基因内删除
--
1
2
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部