包含保守模式编码序列的基因片段被诺美西林抗性选择标记替换。对纯合小鼠大脑和肝脏的样本进行RT-PCR分析显示,这个等位基因没有产生可检测到的转录物。对纯合小鼠胸腺细胞样本的 Western blot 检测也证实,未检测到任何可识别的蛋白质。(来源:J:36821)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
插入,基因内删除
--
1
--
86

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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