一段包含2.3千碱基的5'上游区域和exon 1的前105bp的基因片段被替换成诺卡因选择标记。对来自纯合小鼠肝脏的RNA进行Northern blot分析显示,这种组织中未检测到任何可识别的转录本;然而,在肺、肾、附睾脂肪组织、脾和心脏中,检测到了完整的转录本。(来源:J:56193, J:98856)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129/Sv
Targeted
插入,基因内删除
--
1
6
81

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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