在基因的反转录方向,插入了一个新霉素选择座。Northern印迹分析显示,来自纯合小鼠的总脑RNA中未检测到任何可识别的转录本。对纯合小鼠大脑、新皮层和海马的蛋白质提取物进行 Western 印迹分析也证实,这个等位基因没有产生可检测到的蛋白质。(来源:J:74419)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129X1/SvJ
Targeted
插入
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1
4
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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