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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(Pou3f4-cre)23Cren
Alias:
bcre23
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基础信息
表型特征
文献报道
这个转基因表达的是Pou3f4基因5.6kb的5'上游序列驱动的Cre重组酶基因。推测这种位置效应会在早期胚胎发育中驱动表达,而内源性启动子在此时并不表达。这种菌株可能被用作一种全局的‘删除者’菌株。(来源:J:73526)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
2158500
CD-1
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5
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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