一个PGK-新霉素抗性 cassette替换了大约5kb的序列,包括3-7号外显子,它们编码第二个LIM域、homeodomain以及大部分的羧基端区域。在10dpc的同卵突变体中,RT-PCR分析未检测到编码homeodomain区域的转录本。(来源:J:47316)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1+
Targeted
插入,基因内删除
--
1
5
39

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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