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中文
在第8外显子中插入了新霉素筛选 cassette。删除了一个包含编码关键残基酪氨酸371和histidine 374的104bp DNA片段。对来自纯合小鼠经LPS刺激的巨噬细胞mRNA进行Northern blot分析后，结果显示这个等位基因产生了6.0kb的异常转录本。然而，Western blot分析证实，来自纯合小鼠经LPS刺激的巨噬细胞中，这个等位基因并未产生可检测到的蛋白质。(来源：J:29510)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
