一段包含exon 1和部分内含子1的基因片段被替换了抗氨苄青霉素选择标记。被删除的序列编码了对应蛋白质N端237个氨基酸。对来自纯合小鼠的肾膜进行的 Western blot分析显示,这个等位基因没有检测到蛋白质的产生。(来源:J:74420)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入,基因内删除
--
1
--
29

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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