包含启动子序列和编码首27个氨基酸的编码蛋白序列的基因片段被替换成抗氨苄青霉素抗性基因。来自纯合小鼠大脑、睾丸、心脏和骨骼肌的提取物进行的 Western blot 分析显示,这个等位基因没有检测到可识别的蛋白表达。(来源:J:74250)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129X1/SvJ
Targeted
插入,基因内删除
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1
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8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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