Mecp2^tm1Jae

LoxP sites were inserted flanking exon 3 as follows: A single loxP site was inserted 5' to exon 3 and a loxP-flanked hygromycin and thymidine kinase selection cassette was inserted 3' to exon 3. The selection cassette was removed in ES cells by Cre-mediated recombination prior to the production of chimeric mice, leaving a single loxP site in place of the selection cassette. (J:67909)