Log In|Sign Up
中文
在exon 3的前后分别插入了LoxP位点：在exon 3的5'端插入了一个LoxP，然后在3'端插入了一个由LoxP引导的hygromycin和thymidine kinase的选择性载体。在将这些细胞转化成小鼠胚胎干细胞（ES细胞）后，通过Cre介导的重组移除选择性载体，留下一个LoxP位点，取代了选择性元件。来源：(J:67909)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
