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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Cd2
tm1Litt
Alias:
CD2-
Cd2
tm1Drl
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基础信息
表型特征
文献报道
在第2外显子中插入了新霉素筛选 cassette,插入位置在编码 V-like 区域的氨基酸端。Northern印迹分析显示,这个等位基因没有产生稳定转录本。免疫细胞化学分析显示,淋巴细胞表面没有功能蛋白存在。(来源:J:3149)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2158301
129S2/SvPas
Targeted
插入
--
1
--
10
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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