在exon 3插入PGK-抗氨苄青霉素 resistance cassette导致了基因的突变。使用跨越中间连接器和MH2区域的引物进行RT-PCR分析,没有在纯合突变胚胎中检测到转录。 Western blot实验也未在纯合突变胚胎中检测到任何蛋白质。(来源:J:73279)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
插入
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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