一个lacZ-PGK-hygromycin表达载体替换了1.5kb的序列,包括编码成熟蛋白氨基端区域的exon 5区域。在激活的腹腔巨噬细胞的Northern blot分析中,杂合子突变小鼠中未检测到转录本。(来源:J:47429, J:92002)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入,基因内删除
--
1
--
163

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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