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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Apoe
tm2(APOE*3)Mae
Alias:
Apoe
3
apoE3-KI
Apoe
tm2(APOE)Mae
TgH
APOE3
N8
TRE3
3
TgH/ApoeE3/N8
APOE*3
APOE3
apoE3 TR
apoE TR
E3
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基础信息
表型特征
文献报道
一段包含人类APOE基因(3型亚型)外显子2-4的DNA片段替换了小鼠Apoe基因的相应区域。对纯合小鼠的血浆进行 Western blot 分析显示,这种人类蛋白能从这个等位基因中表达,而内源性小鼠蛋白则无法检测到。(来源:J:41705)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2157240
129P2/OlaHsd
Targeted
插入,基因内删除
--
1
7
163
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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