一段包含人类APOE基因(3型亚型)外显子2-4的DNA片段替换了小鼠Apoe基因的相应区域。对纯合小鼠的血浆进行 Western blot 分析显示,这种人类蛋白能从这个等位基因中表达,而内源性小鼠蛋白则无法检测到。(来源:J:41705)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入,基因内删除
--
1
7
163

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部