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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Ace
tm3Unc
Alias:
Tg(Acedup)2Unc
TgH(Acedup)2Unc
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基础信息
表型特征
文献报道
使用了修复型的靶向载体来诱发基因复制,最终等位基因中存在两个同源的拷贝。在血清和肺组织中的蛋白活性与基因剂量相关联。(来源:J:42519)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2155951
129P2/OlaHsd
Targeted
插入
--
1
4
7
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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