A 4kb genomic fragment containing sequences encoding the bHLH-Zip domains was replaced by a neomycin resistance cassette in the opposite transcriptional orientation. RT-PCR analysis indicated that a truncated transcript is produced from this allele, but no active protein is predicted to be produced. (J:50513)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count