这些品种(Strains 129/Sv, A/J, AKR/J, B10.S/DvTe, BALB/cJ, BALB/cByJ, C57BL/6J, CBA/J, DBA/1J, FVB/NJ, NOD/LtJ, NZB/BInJ和PL/J)在第293位氨基酸位置有一个甘氨酸(Gly), 而对照品种C3H/HeJ, DBA/2J, NZW/LacJ, P/J和SJL的对应位置是天冬氨酸(Aspartic acid)。这个特定的等位基因(allele)使得它们对EAE具有抵抗性,相比SJL/J。(引用: J:34892)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
multiple strains
Not Applicable
未定义
不确定
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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