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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Thbs1
tm1Hyn
Alias:
tbsp1-
TSP-1
-
Thbs1
-
TSP-1
Tsp-1KO
TSP1-
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基础信息
表型特征
文献报道
一个新霉素选择座替换了exon 2、intron 3和exon 3。RNA酶保护分析显示,同源动物的多种组织中未检测到可检测的转录本。 Western分析证实了编码蛋白的缺失。(来源:J:46182)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2154534
129S2/SvPas
Targeted
插入,基因内删除
--
1
--
143
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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