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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Fgfr1
tm2Jrt
Alias:
Fgfr1
n7
n7
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基础信息
表型特征
文献报道
在内皮7号染色体上插入了loxP介导的诺姆西林插件。Northern blot分析显示,纯合小鼠中全长转录本减少了3到5倍,这表明这是一种功能减弱型(或称为假性突变)等位基因。(来源:J:49154)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2153343
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
25
8
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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