在exon 3中插入了新霉素抗性基因座。使用兔抗血清对P4大脑组织进行 Western blot 分析,没有在纯合突变小鼠中检测到蛋白质。对P1纯合突变小鼠的主动脉平滑肌细胞进行免疫组化研究,也未发现蛋白质。(来源:J:54319)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
--
15

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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