将GFP插入到了Hoxa13tm1Mrc这个衍生品的第2外显子内,通过Cre介导的生殖细胞重组,移除了邻近的含 Neo抗性基因的克隆。这个突变体在E10.5-E13.5期胚胎中表达的Hoxa13-GFP融合蛋白表达模式,再现了已发表的Hoxa13 mRNA的表达模式(来源:J:72301)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
2
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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