这段基因的1.2千碱基,包括起始翻译位点,通过同源重组使用了neo衍生的靶向载体进行了删除。 Western blot结果显示,纯合突变动物在背根神经节内不表达蛋白质(来源:J:57887)
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1.2 kb of this gene including the translation initiation site was deleted via homologous recombination with a neo-derived targeting vector. Western blot indicated homozygous mutant animals did not express protein in dorsal root ganglion. (J:57887)