一种新霉素抗性基因座替换了包括3.1kb的序列,包括3号外显子到5号外显子的部分。 Western blot分析在纯合小鼠的脾和胸腺中未检测到蛋白质(J:71005)。
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A neomycin resistance cassette replaced 3.1kb of sequence that includes part of exon 3 through exon 5. Western blot analysis did not detect protein in the spleen and thymus of homozygous mice. (J:71005)