在一种方法中,替换了neomycin-lacZ序列,它位于基因的exon 1位置。对纯合突变小鼠大脑的原位杂交、免疫组化和放射免疫测定都没有检测到 orexin-A 或 orexin-B 肽。(来源:J:57124, J:136109)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
插入,基因内删除
--
1
3
74

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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